Isochromosome 17q in blast crisis of chronic myeloid leukemia and in other hematologic malignancies is the result of clustered breakpoints in 17p11 and is not associated with coding TP53 mutations. [electronic resource]
- Blood Jul 1999
- 225-32 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0006-4971
Adolescent Aged Aged, 80 and over Child, Preschool Chromosomes, Human, Pair 17 Female Genes, Tumor Suppressor Hematologic Neoplasms--genetics Humans Isochromosomes Leukemia, Myelogenous, Chronic, BCR-ABL Positive--genetics Male Middle Aged Mutation Tumor Suppressor Protein p53--genetics