TY  - GEN
AU  - Wei,J
AU  - Wang,D W
AU  - Alings,M
AU  - Fish,F
AU  - Wathen,M
AU  - Roden,D M
AU  - George,A L
TI  - Congenital long-QT syndrome caused by a novel mutation in a conserved acidic domain of the cardiac Na+ channel
SN  - 1524-4539
PY  - 1999///0708
KW  - Adolescent
KW  - Animals
KW  - Base Sequence
KW  - Cloning, Molecular
KW  - Conserved Sequence
KW  - DNA Primers
KW  - Death, Sudden
KW  - Electrocardiography
KW  - Electrophysiology
KW  - Female
KW  - Humans
KW  - Long QT Syndrome
KW  - congenital
KW  - Male
KW  - Membrane Potentials
KW  - drug effects
KW  - Molecular Sequence Data
KW  - Mutagenesis, Site-Directed
KW  - Myocardium
KW  - chemistry
KW  - NAV1.5 Voltage-Gated Sodium Channel
KW  - Oocytes
KW  - physiology
KW  - Pedigree
KW  - Point Mutation
KW  - Polymorphism, Single-Stranded Conformational
KW  - Protein Structure, Tertiary
KW  - Sequence Homology, Amino Acid
KW  - Sodium Channels
KW  - Structure-Activity Relationship
KW  - Tetrodotoxin
KW  - pharmacology
KW  - Xenopus
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1161/01.cir.99.24.3165
ER  -