Mazume, H

Effect of simvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, on alpha-fetoprotein gene expression through interaction with the ras-mediated pathway. [electronic resource] - Journal of hepatology May 1999 - 904-10 p. digital

Publication Type: Journal Article

0168-8278

10.1016/s0168-8278(99)80146-9 doi


Carcinoma, Hepatocellular
Cell Division--drug effects
Chloramphenicol O-Acetyltransferase--genetics
Gene Expression Regulation--drug effects
Genetic Vectors
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Kinetics
Liver Neoplasms
Proto-Oncogene Mas
Recombinant Fusion Proteins--biosynthesis
Serum Albumin--genetics
Signal Transduction
Simvastatin--pharmacology
Transcription, Genetic--drug effects
Transfection
Tumor Cells, Cultured
alpha-Fetoproteins--genetics
ras Proteins--genetics