Lanosterol analogs: dual-action inhibitors of cholesterol biosynthesis. [electronic resource]
- Critical reviews in biochemistry and molecular biology 1999
- 123-40 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
1040-9238
10.1080/10409239991209246 doi
Animals Anticholesteremic Agents--pharmacology CHO Cells Coronary Disease--metabolism Cricetinae Cytochrome P-450 Enzyme System--physiology Dose-Response Relationship, Drug Hydroxymethylglutaryl CoA Reductases--physiology Inhibitory Concentration 50 Ketones--chemistry Lanosterol--analogs & derivatives Microsomes, Liver--drug effects Models, Biological Models, Chemical Oxidoreductases--physiology Oximes--chemistry RNA Processing, Post-Transcriptional Rats Receptors, LDL--genetics Sterol 14-Demethylase Time Factors