TY - GEN AU - Chan,V J AU - Selzer,P M AU - McKerrow,J H AU - Sakanari,J A TI - Expression and alteration of the S2 subsite of the Leishmania major cathepsin B-like cysteine protease SN - 0264-6021 PY - 1999///0630 KW - Amino Acid Sequence KW - Animals KW - Binding Sites KW - Cathepsin B KW - antagonists & inhibitors KW - Coumarins KW - metabolism KW - Dipeptides KW - pharmacology KW - Glutamic Acid KW - genetics KW - Glycine KW - Humans KW - Hydrogen-Ion Concentration KW - Kinetics KW - Leishmania major KW - enzymology KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - Mutation KW - Pichia KW - Rats KW - Recombinant Proteins KW - biosynthesis KW - Sequence Homology, Amino Acid KW - Structure-Activity Relationship KW - Substrate Specificity KW - Sulfones N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -