Novel derivatives of 2-pyridinemethylamine as selective, potent, and orally active agonists at 5-HT1A receptors. [electronic resource]
- Journal of medicinal chemistry May 1999
- 1648-60 p. digital
Publication Type: Journal Article
0022-2623
10.1021/jm9806906 doi
Administration, Oral Aminopyridines--chemical synthesis Animals Antidepressive Agents--chemical synthesis Binding, Competitive Cell Line Cyclic AMP--biosynthesis Drug Evaluation, Preclinical HeLa Cells Humans Ligands Male Motor Activity--drug effects Piperidines--chemical synthesis Pyridines--chemical synthesis Radioligand Assay Rats Rats, Wistar Receptors, Serotonin--drug effects Receptors, Serotonin, 5-HT1 Serotonin Receptor Agonists--chemical synthesis Structure-Activity Relationship