Machiels, J P

Retrovirus-mediated gene transfer of the human multidrug resistance-associated protein into hematopoietic cells protects mice from chemotherapy-induced leukopenia. [electronic resource] - Human gene therapy Mar 1999 - 801-11 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1043-0342

10.1089/10430349950018553 doi


ATP-Binding Cassette Transporters--genetics
Animals
Antineoplastic Agents--adverse effects
Blotting, Southern
Bone Marrow Cells--metabolism
Dose-Response Relationship, Drug
Doxorubicin--adverse effects
Flow Cytometry
Gene Transfer Techniques
Hematopoietic Stem Cells--metabolism
Humans
Leukocytes--drug effects
Leukopenia--chemically induced
Male
Mice
Mice, Inbred C57BL
Multidrug Resistance-Associated Proteins
Retroviridae--genetics
Reverse Transcriptase Polymerase Chain Reaction
Time Factors