Retrovirus-mediated gene transfer of the human multidrug resistance-associated protein into hematopoietic cells protects mice from chemotherapy-induced leukopenia. [electronic resource]
- Human gene therapy Mar 1999
- 801-11 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1043-0342
10.1089/10430349950018553 doi
ATP-Binding Cassette Transporters--genetics Animals Antineoplastic Agents--adverse effects Blotting, Southern Bone Marrow Cells--metabolism Dose-Response Relationship, Drug Doxorubicin--adverse effects Flow Cytometry Gene Transfer Techniques Hematopoietic Stem Cells--metabolism Humans Leukocytes--drug effects Leukopenia--chemically induced Male Mice Mice, Inbred C57BL Multidrug Resistance-Associated Proteins Retroviridae--genetics Reverse Transcriptase Polymerase Chain Reaction Time Factors