Zhang, M <br/><br/>
Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 2. Sidechain optimization and demonstration of in vivo efficacy.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Mar 1999 
 - 775-80 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0960-894X 
<br/><br/><label>Standard No.: </label>10.1016/s0960-894x(99)00074-8  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anticoagulants--chemistry<br/>Binding Sites<br/>Crystallography, X-Ray<br/>Disease Models, Animal<br/>Humans<br/>Models, Molecular<br/>Rats<br/>Structure-Activity Relationship<br/>Thiophenes--chemistry<br/>Thrombin--antagonists & inhibitors<br/>Thrombosis--drug therapy