TY  - GEN
AU  - Brown,G R
AU  - Hollinshead,D M
AU  - Stokes,E S
AU  - Clarke,D S
AU  - Eakin,M A
AU  - Foubister,A J
AU  - Glossop,S C
AU  - Griffiths,D
AU  - Johnson,M C
AU  - McTaggart,F
AU  - Mirrlees,D J
AU  - Smith,G J
AU  - Wood,R
TI  - Quinuclidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase: optimization from lipid profiles
SN  - 0022-2623
PY  - 1999///0520
KW  - Administration, Oral
KW  - Animals
KW  - Anticholesteremic Agents
KW  - chemical synthesis
KW  - Callithrix
KW  - Chromatography, High Pressure Liquid
KW  - Enzyme Inhibitors
KW  - Humans
KW  - In Vitro Techniques
KW  - Intramolecular Transferases
KW  - antagonists & inhibitors
KW  - Lipid Metabolism
KW  - Lipids
KW  - analysis
KW  - Liver
KW  - chemistry
KW  - Male
KW  - Microsomes
KW  - drug effects
KW  - Quinuclidines
KW  - Rats
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm990038q
ER  -