Jacobsen, E J <br/><br/>
Piperazine imidazo[1,5-a]quinoxaline ureas as high-affinity GABAA ligands of dual functionality.  [electronic resource] 

 -  Journal of medicinal chemistry  Apr 1999 
 - 1123-44 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm9801307  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anti-Anxiety Agents--chemical synthesis<br/>Anticonvulsants--chemical synthesis<br/>Anxiety--metabolism<br/>Biological Availability<br/>Cell Line<br/>Cerebellum--drug effects<br/>Convulsants--toxicity<br/>Cyclic GMP--antagonists & inhibitors<br/>Drug Evaluation, Preclinical<br/>GABA Agonists--chemical synthesis<br/>Imidazoles--chemical synthesis<br/>In Vitro Techniques<br/>Ligands<br/>Male<br/>Mice<br/>Models, Molecular<br/>Molecular Conformation<br/>Pentylenetetrazole--toxicity<br/>Piperazines--chemical synthesis<br/>Quinoxalines--chemical synthesis<br/>Rats<br/>Rats, Inbred F344<br/>Rats, Sprague-Dawley<br/>Receptors, GABA-A--metabolism<br/>Seizures--chemically induced<br/>Structure-Activity Relationship<br/>Urea--analogs & derivatives