TY - GEN AU - Li,Q AU - Van Antwerp,D AU - Mercurio,F AU - Lee,K F AU - Verma,I M TI - Severe liver degeneration in mice lacking the IkappaB kinase 2 gene SN - 0036-8075 PY - 1999///0504 KW - Animals KW - Apoptosis KW - Cell Line KW - DNA-Binding Proteins KW - metabolism KW - Embryonic and Fetal Development KW - Gene Targeting KW - I-kappa B Kinase KW - I-kappa B Proteins KW - Interleukin-1 KW - pharmacology KW - Liver KW - cytology KW - Mice KW - NF-kappa B KW - Phosphorylation KW - Polymerase Chain Reaction KW - Protein Serine-Threonine Kinases KW - genetics KW - Receptors, Tumor Necrosis Factor KW - Recombinant Fusion Proteins KW - Sequence Deletion KW - Signal Transduction KW - Transcription Factor RelA KW - Transcription Factors KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1126/science.284.5412.321 ER -