TY - GEN AU - Kellenberger,S AU - Gautschi,I AU - Schild,L TI - A single point mutation in the pore region of the epithelial Na+ channel changes ion selectivity by modifying molecular sieving SN - 0027-8424 PY - 1999///0512 KW - Amino Acid Sequence KW - Animals KW - Cations, Divalent KW - metabolism KW - Cations, Monovalent KW - Conserved Sequence KW - Epithelial Sodium Channels KW - Female KW - Macromolecular Substances KW - Membrane Potentials KW - drug effects KW - Models, Molecular KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - Oocytes KW - Point Mutation KW - Protein Conformation KW - Rats KW - Recombinant Proteins KW - Sequence Alignment KW - Sequence Homology, Amino Acid KW - Serine KW - Sodium Channels KW - chemistry KW - Xenopus laevis N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.96.7.4170 ER -