Colitis-inducing potency of CD4+ T cells in immunodeficient, adoptive hosts depends on their state of activation, IL-12 responsiveness, and CD45RB surface phenotype. [electronic resource]
- Journal of immunology (Baltimore, Md. : 1950) Mar 1999
- 3702-10 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-1767
Adoptive Transfer Animals CD4-Positive T-Lymphocytes--immunology DNA-Binding Proteins--genetics Female Immunophenotyping Inflammatory Bowel Diseases--etiology Interferon-gamma--biosynthesis Interleukin-12--pharmacology Interphase--immunology Leukocyte Common Antigens--biosynthesis Lymphocyte Activation Mice Mice, Inbred BALB C Mice, Knockout Mice, SCID STAT4 Transcription Factor Severe Combined Immunodeficiency--immunology Signal Transduction--genetics Th1 Cells--pathology Trans-Activators--genetics Tumor Necrosis Factor-alpha--biosynthesis