TY  - GEN
AU  - Haining,R L
AU  - Jones,J P
AU  - Henne,K R
AU  - Fisher,M B
AU  - Koop,D R
AU  - Trager,W F
AU  - Rettie,A E
TI  - Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding
SN  - 0006-2960
PY  - 1999///0415
KW  - Arachidonic Acid
KW  - metabolism
KW  - Aryl Hydrocarbon Hydroxylases
KW  - Binding Sites
KW  - genetics
KW  - Blotting, Western
KW  - Catalysis
KW  - Cytochrome P-450 Enzyme Inhibitors
KW  - Cytochrome P-450 Enzyme System
KW  - chemistry
KW  - Diclofenac
KW  - Kinetics
KW  - Lauric Acids
KW  - Leucine
KW  - Mutagenesis, Site-Directed
KW  - Phenylalanine
KW  - Protein Structure, Secondary
KW  - Static Electricity
KW  - Steroid 16-alpha-Hydroxylase
KW  - Steroid Hydroxylases
KW  - antagonists & inhibitors
KW  - Substrate Specificity
KW  - drug effects
KW  - Sulfaphenazole
KW  - pharmacology
KW  - Warfarin
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1021/bi982161+
ER  -