Activation of the human RANTES gene promoter in a macrophage cell line by lipopolysaccharide is dependent on stress-activated protein kinases and the IkappaB kinase cascade: implications for exacerbation of allergic inflammation by environmental pollutants. [electronic resource]
- Clinical immunology (Orlando, Fla.) Mar 1999
- 287-301 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
1521-6616
10.1006/clim.1998.4659 doi
Air Pollutants--immunology Calcium-Calmodulin-Dependent Protein Kinases--metabolism Chemokine CCL5--genetics Genes, Reporter Humans Hydroquinones--immunology Hypersensitivity--immunology I-kappa B Kinase JNK Mitogen-Activated Protein Kinases Lipopolysaccharides--immunology Macrophages--immunology Mitogen-Activated Protein Kinases NF-kappa B--metabolism Oxidation-Reduction Promoter Regions, Genetic Protein Binding Protein Serine-Threonine Kinases--metabolism RNA, Messenger--analysis Response Elements Signal Transduction Transcription Factor AP-1--metabolism Transcriptional Activation