TY - GEN AU - Shi,J AU - McAtee,J J AU - Schlueter Wirtz,S AU - Tharnish,P AU - Juodawlkis,A AU - Liotta,D C AU - Schinazi,R F TI - Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase SN - 0022-2623 PY - 1999///0413 KW - Animals KW - Anti-HIV Agents KW - chemical synthesis KW - Antineoplastic Agents KW - Drug Screening Assays, Antitumor KW - HIV Reverse Transcriptase KW - antagonists & inhibitors KW - Humans KW - Organophosphates KW - Rats KW - Reverse Transcriptase Inhibitors KW - Stereoisomerism KW - Structure-Activity Relationship KW - Tumor Cells, Cultured KW - Zalcitabine KW - analogs & derivatives N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/jm980510s ER -