TY - GEN AU - Herben,V M AU - Panday,V R AU - Richel,D J AU - Schellens,J H AU - van der Vange,N AU - Rosing,H AU - Beusenberg,F D AU - Hearn,S AU - Doyle,E AU - Beijnen,J H AU - ten Bokkel Huinink,W W TI - Phase I and pharmacologic study of the combination of paclitaxel, cisplatin, and topotecan administered intravenously every 21 days as first-line therapy in patients with advanced ovarian cancer SN - 0732-183X PY - 1999///0316 KW - Adult KW - Aged KW - Antineoplastic Combined Chemotherapy Protocols KW - adverse effects KW - Blood Cell Count KW - Cisplatin KW - administration & dosage KW - Fatigue KW - chemically induced KW - Female KW - Granulocyte Colony-Stimulating Factor KW - Humans KW - Infusions, Intravenous KW - Middle Aged KW - Nausea KW - Neoplasm Staging KW - Neutropenia KW - Ovarian Neoplasms KW - drug therapy KW - Paclitaxel KW - Thrombocytopenia KW - Topotecan N1 - Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1200/JCO.1999.17.3.747 ER -