TY  - GEN
AU  - Yin,M B
AU  - Guo,B
AU  - Panadero,A
AU  - Frank,C
AU  - Wrzosek,C
AU  - Slocum,H K
AU  - Rustum,Y M
TI  - Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex
SN  - 0014-4827
PY  - 1999///0317
KW  - CDC2-CDC28 Kinases
KW  - Carrier Proteins
KW  - Cell Cycle
KW  - drug effects
KW  - Cell Cycle Proteins
KW  - Cyclin A
KW  - chemistry
KW  - Cyclin E
KW  - metabolism
KW  - Cyclin-Dependent Kinase 2
KW  - Cyclin-Dependent Kinases
KW  - antagonists & inhibitors
KW  - DNA
KW  - DNA Fragmentation
KW  - DNA, Neoplasm
KW  - DNA-Binding Proteins
KW  - E2F Transcription Factors
KW  - E2F1 Transcription Factor
KW  - Enzyme Activation
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Growth Inhibitors
KW  - Humans
KW  - Macromolecular Substances
KW  - Protein Serine-Threonine Kinases
KW  - Quinazolines
KW  - Retinoblastoma-Binding Protein 1
KW  - Thiophenes
KW  - Thymidine
KW  - physiology
KW  - Thymidylate Synthase
KW  - Transcription Factor DP1
KW  - Transcription Factors
KW  - biosynthesis
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1006/excr.1998.4346
ER  -