Yin, M B <br/><br/>
Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.  [electronic resource] 

 -  Experimental cell research  Feb 1999 
 - 189-99 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0014-4827 
<br/><br/><label>Standard No.: </label>10.1006/excr.1998.4346  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>CDC2-CDC28 Kinases<br/>Carrier Proteins<br/>Cell Cycle--drug effects<br/>Cell Cycle Proteins<br/>Cyclin A--chemistry<br/>Cyclin E--metabolism<br/>Cyclin-Dependent Kinase 2<br/>Cyclin-Dependent Kinases--antagonists & inhibitors<br/>DNA--antagonists & inhibitors<br/>DNA Fragmentation--drug effects<br/>DNA, Neoplasm--metabolism<br/>DNA-Binding Proteins<br/>E2F Transcription Factors<br/>E2F1 Transcription Factor<br/>Enzyme Activation--drug effects<br/>Enzyme Inhibitors--pharmacology<br/>Growth Inhibitors--pharmacology<br/>Humans<br/>Macromolecular Substances<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Quinazolines--pharmacology<br/>Retinoblastoma-Binding Protein 1<br/>Thiophenes--pharmacology<br/>Thymidine--physiology<br/>Thymidylate Synthase--antagonists & inhibitors<br/>Transcription Factor DP1<br/>Transcription Factors--biosynthesis<br/>Tumor Cells, Cultured