Human single-chain Fv immunoconjugates targeted to a melanoma-associated chondroitin sulfate proteoglycan mediate specific lysis of human melanoma cells by natural killer cells and complement. [electronic resource]
Producer: 19990325Description: 1627-32 p. digitalISSN:- 0027-8424
- Animals
- Base Sequence
- CHO Cells
- Cell Line
- Cells, Cultured
- Chondroitin Sulfate Proteoglycans -- immunology
- Chromatography, Liquid
- Complement System Proteins -- immunology
- Cricetinae
- Cytotoxicity, Immunologic
- Drosophila melanogaster
- Endothelium, Vascular -- immunology
- Humans
- Immunoconjugates -- isolation & purification
- Immunoglobulin Fragments -- genetics
- Immunoglobulin G -- genetics
- Immunoglobulin Variable Region -- genetics
- Killer Cells, Natural -- immunology
- Mass Spectrometry
- Melanoma -- immunology
- Molecular Sequence Data
- Restriction Mapping
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Transfection
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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