Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group Study. [electronic resource]
Producer: 19990513Description: 507-19 p. digitalISSN:- 1042-8194
- Adolescent
- Aneuploidy
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Bone Marrow -- chemistry
- Child
- Child, Preschool
- Chromosomes, Human, Pair 10
- Chromosomes, Human, Pair 4
- Female
- Folic Acid -- metabolism
- Humans
- Male
- Methotrexate -- analogs & derivatives
- Neoplastic Stem Cells -- metabolism
- Peptide Synthases -- metabolism
- Polyglutamic Acid -- analogs & derivatives
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma -- genetics
- Prognosis
- Trisomy
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Publication Type: Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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