p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption. [electronic resource]
Producer: 19990210Description: 205-15 p. digitalISSN:- 0270-7306
- CDC2-CDC28 Kinases
- Cyclin B -- metabolism
- Cyclin B1
- Cyclin E
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinase 4
- Cyclin-Dependent Kinase 6
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclin-Dependent Kinases -- metabolism
- Cyclins -- genetics
- DNA Replication
- Enzyme Inhibitors
- G1 Phase
- Humans
- Mutagenesis
- Proliferating Cell Nuclear Antigen -- metabolism
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins
- S Phase
- Spindle Apparatus
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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