Cardioprotective actions of KC 12291. I. Inhibition of voltage-gated Na+ channels in ischemia delays myocardial Na+ overload. [electronic resource]
Producer: 19990204Description: 547-53 p. digitalISSN:- 0028-1298
- Animals
- Cardiovascular Agents -- pharmacology
- Electric Stimulation
- Electrocardiography -- drug effects
- Female
- Guinea Pigs
- Heart -- drug effects
- Heart Atria -- cytology
- Heart Ventricles -- cytology
- Hypoxia
- In Vitro Techniques
- Ion Channel Gating -- drug effects
- Male
- Membrane Potentials -- drug effects
- Myocardial Contraction -- drug effects
- Myocardial Ischemia -- metabolism
- Myocardium -- cytology
- Oxygen
- Patch-Clamp Techniques
- Perfusion
- Rats
- Rats, Wistar
- Sodium -- metabolism
- Sodium Channels -- drug effects
- Thiadiazoles -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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