Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. [electronic resource]
Producer: 19981120Description: 84-8 p. digitalISSN:- 0028-0836
- Breast -- cytology
- Cell Transformation, Neoplastic
- Cell Transformation, Viral
- Cells, Cultured
- Cellular Senescence -- physiology
- Cyclin-Dependent Kinase Inhibitor p16 -- antagonists & inhibitors
- DNA-Binding Proteins
- Enzyme Induction
- Humans
- Keratinocytes -- cytology
- Oncogene Proteins, Viral -- physiology
- Proteins -- physiology
- RNA
- Repressor Proteins
- Retinoblastoma Protein -- antagonists & inhibitors
- Telomerase -- physiology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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