Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation. [electronic resource]
Producer: 19990209Description: 1429-36 p. digitalISSN:- 1078-0432
- Breast Neoplasms -- metabolism
- Cell Adhesion -- drug effects
- Cell Division -- drug effects
- Cell Transformation, Neoplastic -- metabolism
- Estrogens -- pharmacology
- Female
- Genetic Vectors
- Humans
- Insulin Receptor Substrate Proteins
- Insulin-Like Growth Factor I -- metabolism
- Neoplasm Proteins -- genetics
- Phosphoproteins -- genetics
- Receptor, Insulin -- metabolism
- Transfection
- Tumor Cells, Cultured -- drug effects
- Tumor Stem Cell Assay
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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