A pilot clinical/pharmacological study of the protein kinase C-specific inhibitor safingol alone and in combination with doxorubicin. [electronic resource]
Producer: 19990218Description: 537-43 p. digitalISSN:- 1078-0432
- Adult
- Aged
- Antineoplastic Agents -- administration & dosage
- Antineoplastic Combined Chemotherapy Protocols -- administration & dosage
- Dose-Response Relationship, Drug
- Doxorubicin -- administration & dosage
- Drug Administration Schedule
- Enzyme Inhibitors -- administration & dosage
- Female
- Humans
- Infusions, Intravenous
- Leukopenia -- chemically induced
- Male
- Metabolic Clearance Rate
- Middle Aged
- Neoplasms -- blood
- Pilot Projects
- Protein Kinase C -- antagonists & inhibitors
- Regression Analysis
- Sphingosine -- administration & dosage
- Thrombocytopenia -- chemically induced
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Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article
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