Human lymphoblastoid cell lines expressing mutant p53 exhibit decreased sensitivity to cisplatin-induced cytotoxicity. [electronic resource]
Producer: 19981116Description: 2339-50 p. digitalISSN:- 0950-9232
- Antineoplastic Agents -- pharmacology
- Apoptosis
- B-Lymphocytes -- drug effects
- Cell Line -- drug effects
- Cisplatin -- pharmacology
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- metabolism
- G1 Phase -- drug effects
- Gamma Rays
- Humans
- Lymphoma, Large B-Cell, Diffuse -- metabolism
- Mutation
- Neoplasm Proteins -- drug effects
- Nuclear Proteins
- Poly(ADP-ribose) Polymerases -- drug effects
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Proto-Oncogene Proteins c-mdm2
- RNA, Messenger -- drug effects
- S Phase -- drug effects
- Transfection
- Tumor Cells, Cultured -- drug effects
- Tumor Suppressor Protein p53 -- drug effects
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Publication Type: Journal Article
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