Decreased benzodiazepine binding with little effect on gamma-aminobutyric acid binding in rat brain after treatment with antisense oligodeoxynucleotide to the gamma-aminobutyric acidA receptor gamma-2 subunit. [electronic resource]
Producer: 19981207Description: 752-9 p. digitalISSN:- 0022-3565
- Animals
- Base Sequence
- Benzodiazepines -- metabolism
- Blotting, Western
- Bridged Bicyclo Compounds, Heterocyclic -- metabolism
- Cerebellum -- drug effects
- Flunitrazepam -- metabolism
- Male
- Muscimol -- metabolism
- Oligonucleotides, Antisense -- pharmacology
- Protein Binding
- Radioligand Assay
- Rats
- Rats, Sprague-Dawley
- Receptors, GABA-A -- genetics
- Tritium
- Xanthines -- metabolism
- gamma-Aminobutyric Acid -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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