Chronic hyperammonemia impairs the glutamate-nitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivo. [electronic resource]
Producer: 19990607Description: 3201-9 p. digitalISSN:- 0953-816X
- Ammonia -- blood
- Animals
- Cell Death -- drug effects
- Cells, Cultured
- Cerebellum -- cytology
- Cyclic GMP -- analysis
- Dialysis Solutions -- chemistry
- Dose-Response Relationship, Drug
- Extracellular Space -- chemistry
- Glutamic Acid -- metabolism
- Male
- Microdialysis
- N-Methylaspartate -- pharmacology
- Neurons -- cytology
- Nitric Oxide -- metabolism
- Perfusion
- Rats
- Rats, Wistar
- Receptors, N-Methyl-D-Aspartate -- metabolism
- Signal Transduction -- drug effects
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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