Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. [electronic resource]
Producer: 19981022Description: 12022-7 p. digitalISSN:- 0027-8424
- Animals
- Antineoplastic Agents -- chemistry
- Binding Sites -- genetics
- Cell Line
- Cysteine -- chemistry
- Enzyme Inhibitors -- chemistry
- ErbB Receptors -- antagonists & inhibitors
- Humans
- Mice
- Mice, Nude
- Models, Molecular
- Mutagenesis, Site-Directed
- Neoplasm Transplantation
- Neoplasms, Experimental -- drug therapy
- Protein Conformation
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Quinazolines -- chemistry
- Receptor, ErbB-2 -- antagonists & inhibitors
- Recombinant Fusion Proteins -- antagonists & inhibitors
- Transplantation, Heterologous
- Tumor Cells, Cultured
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Publication Type: Journal Article
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