Upregulation of interleukin 6 and granulocyte colony-stimulating factor receptors by transcription factor CCAAT enhancer binding protein alpha (C/EBP alpha) is critical for granulopoiesis. [electronic resource]
Producer: 19981015Description: 1173-84 p. digitalISSN:- 0022-1007
- Animals
- CCAAT-Enhancer-Binding Proteins
- Cell Differentiation -- genetics
- Colony-Forming Units Assay
- DNA-Binding Proteins -- genetics
- Drug Synergism
- Enhancer Elements, Genetic
- Fetus
- Granulocytes -- physiology
- Hematopoiesis -- drug effects
- Hematopoietic Stem Cells -- drug effects
- Humans
- Interleukin-6 -- pharmacology
- Liver -- cytology
- Mice
- Mice, Knockout
- Mutation
- Nuclear Proteins -- genetics
- RNA, Messenger -- antagonists & inhibitors
- Receptors, Granulocyte Colony-Stimulating Factor -- antagonists & inhibitors
- Receptors, Interleukin-6 -- antagonists & inhibitors
- Solubility
- Transcription Factors -- genetics
- Up-Regulation -- genetics
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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