Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules. [electronic resource]
Producer: 19981007Description: 299-309 p. digitalISSN:- 0003-9861
- Amino Acid Sequence
- Animals
- Binding, Competitive
- Calcium-Calmodulin-Dependent Protein Kinase Type 2
- Calcium-Calmodulin-Dependent Protein Kinases -- metabolism
- Cyclin-Dependent Kinase 5
- Cyclin-Dependent Kinases
- Glycogen Synthase Kinase 3
- Humans
- Isomerism
- Microtubule-Associated Proteins
- Microtubules -- metabolism
- Molecular Sequence Data
- Phosphorylation
- Protein Binding
- Protein Serine-Threonine Kinases -- metabolism
- Rats
- Serine -- metabolism
- Threonine -- metabolism
- tau Proteins -- antagonists & inhibitors
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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