Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe. [electronic resource]
Producer: 19990205Description: 12536-45 p. digitalISSN:- 0006-2960
- Aflatoxin B1 -- metabolism
- Amino Acid Sequence
- Animals
- Aryl Hydrocarbon Hydroxylases
- Binding Sites -- genetics
- Computer Simulation
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- chemistry
- Cytochromes b5 -- chemistry
- Humans
- Male
- Microsomes, Liver -- enzymology
- Models, Molecular
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- NADPH-Ferrihemoprotein Reductase -- chemistry
- Oxidoreductases, N-Demethylating -- chemistry
- Rats
- Recombinant Proteins -- biosynthesis
- Stereoisomerism
- Steroid Hydroxylases -- chemistry
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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