Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. [electronic resource]
Producer: 19980921Description: 491-501 p. digitalISSN:- 0092-8674
- Animals
- Apoptosis -- physiology
- BH3 Interacting Domain Death Agonist Protein
- Carrier Proteins -- metabolism
- Caspase 8
- Caspase 9
- Caspases
- Cell Nucleus -- pathology
- Cell Size
- Cysteine Endopeptidases -- metabolism
- Cytochrome c Group -- metabolism
- Humans
- Mice
- Mitochondria -- ultrastructure
- Peptide Fragments -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Signal Transduction
- Substrate Specificity
- Tumor Necrosis Factor-alpha -- metabolism
- bcl-X Protein
- fas Receptor -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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