p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway. [electronic resource]
Producer: 19981013Description: 24057-64 p. digitalISSN:- 0021-9258
- Acetylcysteine -- analogs & derivatives
- Animals
- COS Cells
- Cells, Cultured
- Cerebral Cortex -- metabolism
- Cyclin-Dependent Kinase 5
- Cyclin-Dependent Kinases
- Cysteine Endopeptidases -- metabolism
- Embryo, Mammalian
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Half-Life
- Humans
- Kinetics
- Mammals
- Mice
- Multienzyme Complexes -- metabolism
- Nerve Tissue Proteins -- genetics
- Neurons -- cytology
- Polymerase Chain Reaction
- Proteasome Endopeptidase Complex
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Purines -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Recombinant Proteins -- metabolism
- Roscovitine
- Sequence Deletion
- Transfection
- Ubiquitins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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