CXCR1 and CXCR2 are rapidly down-modulated by bacterial endotoxin through a unique agonist-independent, tyrosine kinase-dependent mechanism. [electronic resource]
Producer: 19980827Description: 1930-8 p. digitalISSN:- 0022-1767
- Antigens, CD -- biosynthesis
- Benzoquinones
- Down-Regulation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Enzyme Precursors -- metabolism
- GTP-Binding Proteins -- physiology
- Genistein -- pharmacology
- Humans
- Interleukin-1 -- metabolism
- Interleukin-8 -- metabolism
- Intracellular Signaling Peptides and Proteins
- Lactams, Macrocyclic
- Lipopolysaccharides -- pharmacology
- Molecular Weight
- Neutrophil Activation -- immunology
- Neutrophils -- enzymology
- Phosphorylation
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Quinones -- pharmacology
- Receptors, Chemokine -- agonists
- Receptors, Interleukin -- agonists
- Receptors, Interleukin-8A
- Receptors, Interleukin-8B
- Rifabutin -- analogs & derivatives
- Signal Transduction -- drug effects
- Syk Kinase
- Time Factors
- Tumor Necrosis Factor-alpha -- metabolism
- Tyrosine -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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