Human N-demethylation of (S)-mephenytoin by cytochrome P450s 2C9 and 2B6. [electronic resource]
Producer: 19980831Description: 775-8 p. digitalISSN:- 0090-9556
- Anticonvulsants -- metabolism
- Aryl Hydrocarbon Hydroxylases
- Cytochrome P-450 CYP2B6
- Cytochrome P-450 CYP2C9
- Cytochrome P-450 Enzyme System -- metabolism
- Humans
- Isoenzymes -- metabolism
- Kinetics
- Mephenytoin -- analogs & derivatives
- Methylation
- Microsomes, Liver -- metabolism
- Oxidoreductases, N-Demethylating -- metabolism
- Phenotype
- Stereoisomerism
- Steroid 16-alpha-Hydroxylase
- Steroid Hydroxylases -- metabolism
- Substrate Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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