Permanent exposure of mucin-secreting HT-29 cells to benzyl-N-acetyl-alpha-D-galactosaminide induces abnormal O-glycosylation of mucins and inhibits constitutive and stimulated MUC5AC secretion. [electronic resource]
Producer: 19981008Description: 283-95 p. digitalISSN:- 0264-6021
- Acetylgalactosamine -- analogs & derivatives
- Adenocarcinoma
- Benzyl Compounds -- pharmacology
- Carbohydrate Sequence
- Colonic Neoplasms
- Galactose -- metabolism
- Glycosylation
- Glycosyltransferases -- metabolism
- Humans
- Kinetics
- Microsomes -- enzymology
- Molecular Sequence Data
- Mucin 5AC
- Mucins -- biosynthesis
- Nuclear Magnetic Resonance, Biomolecular
- Oligosaccharides -- biosynthesis
- Polymerase Chain Reaction
- Sialic Acids -- metabolism
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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