Inhibition of renal arachidonic acid omega-hydroxylase activity with ABT reduces blood pressure in the SHR. [electronic resource]
Producer: 19980916Description: R426-38 p. digitalISSN:- 0002-9513
- Animals
- Blood Pressure -- drug effects
- Cytochrome P-450 CYP4A
- Cytochrome P-450 Enzyme Inhibitors
- Hydroxyeicosatetraenoic Acids -- metabolism
- Hypertension -- enzymology
- Kidney -- enzymology
- Kidney Cortex -- enzymology
- Kidney Medulla -- enzymology
- Kinetics
- Male
- Microsomes -- enzymology
- Microsomes, Liver -- enzymology
- Mixed Function Oxygenases -- antagonists & inhibitors
- Rats
- Rats, Inbred SHR
- Rats, Sprague-Dawley
- Reference Values
- Triazoles -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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