Cyclin A levels, the duration of S phase and sensitivity to a chemotherapeutic agent are altered in fibroblasts cultured on a fibronectin matrix. [electronic resource]
Producer: 19980904Description: 549-55 p. digitalISSN:- 1019-6439
- 3T3 Cells -- cytology
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- CDC2-CDC28 Kinases
- Camptothecin -- pharmacology
- Carrier Proteins
- Cell Cycle Proteins
- Cells, Cultured
- Cyclin A -- biosynthesis
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinases -- metabolism
- DNA-Binding Proteins
- E2F Transcription Factors
- E2F1 Transcription Factor
- Extracellular Matrix -- physiology
- Fibronectins -- pharmacology
- Mice
- Mutation
- Protein Serine-Threonine Kinases -- metabolism
- Retinoblastoma-Binding Protein 1
- S Phase -- drug effects
- Sensitivity and Specificity
- Transcription Factor DP1
- Transcription Factors -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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