Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors. [electronic resource]
Producer: 19980929Description: 643-59 p. digitalISSN:- 0968-0896
- Animals
- Antineoplastic Agents -- chemical synthesis
- Drug Design
- Drug Screening Assays, Antitumor
- Enzyme Inhibitors -- chemical synthesis
- Hydroxymethyl and Formyl Transferases -- antagonists & inhibitors
- Mice
- Phosphoribosylaminoimidazolecarboxamide Formyltransferase
- Phosphoribosylglycinamide Formyltransferase
- Pyrimidines -- chemical synthesis
- Quinazolines -- chemical synthesis
- Structure-Activity Relationship
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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