The nematode degenerin UNC-105 forms ion channels that are activated by degeneration- or hypercontraction-causing mutations. [electronic resource]
Producer: 19980724Description: 1231-41 p. digitalISSN:- 0896-6273
- Amiloride -- pharmacology
- Animals
- Apoptosis -- physiology
- Caenorhabditis elegans Proteins
- Cell Size -- physiology
- Cell Survival -- physiology
- Cells, Cultured
- Diuretics -- pharmacology
- Gene Expression -- physiology
- Helminth Proteins -- genetics
- Humans
- Ion Channel Gating -- drug effects
- Ion Channels -- genetics
- Kidney -- cytology
- Microscopy, Electron
- Mutation -- physiology
- Oocytes -- physiology
- Patch-Clamp Techniques
- Phenotype
- Sodium Channels -- genetics
- Vacuoles -- pathology
- Xenopus laevis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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