Treatment of rats during pubertal development with 2,3,7,8-tetrachlorodibenzo-p-dioxin alters both signaling kinase activities and epidermal growth factor receptor binding in the testis and the motility and acrosomal reaction of sperm. [electronic resource]
Producer: 19980805Description: 427-42 p. digitalISSN:- 0041-008X
- Acrosome -- drug effects
- Animals
- Binding, Competitive
- CSK Tyrosine-Protein Kinase
- Calcium-Calmodulin-Dependent Protein Kinases -- analysis
- Cyclic AMP-Dependent Protein Kinases -- analysis
- ErbB Receptors -- drug effects
- Male
- Mitogen-Activated Protein Kinase 1
- Polychlorinated Dibenzodioxins -- toxicity
- Protein Kinase C -- analysis
- Protein Kinases -- analysis
- Protein-Tyrosine Kinases -- analysis
- Rats
- Rats, Sprague-Dawley
- Sexual Maturation
- Sperm Count
- Sperm Motility -- drug effects
- Testis -- drug effects
- src Homology Domains
- src-Family Kinases
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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