Alcohol-mediated increases in acetaminophen hepatotoxicity: role of CYP2E and CYP3A. [electronic resource]
Producer: 19980702Description: 1557-65 p. digitalISSN:- 0006-2952
- Acetaminophen -- adverse effects
- Animals
- Aryl Hydrocarbon Hydroxylases
- Biotransformation
- Cytochrome P-450 CYP2E1 -- metabolism
- Cytochrome P-450 CYP2E1 Inhibitors
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- metabolism
- Drug Synergism
- Enzyme Inhibitors -- pharmacology
- Ethanol -- adverse effects
- Liver -- drug effects
- Oxidoreductases, N-Demethylating -- antagonists & inhibitors
- Substance Withdrawal Syndrome
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review
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