Induction of p53 without increase in p21WAF1 in betulinic acid-mediated cell death is preferential for human metastatic melanoma. [electronic resource]
Producer: 19980625Description: 399-406 p. digitalISSN:- 1044-5498
- Antineoplastic Agents, Phytogenic -- pharmacology
- Cell Death -- drug effects
- Cyclin D1 -- metabolism
- Cyclin D3
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- biosynthesis
- DNA Damage
- Drug Resistance, Neoplasm
- Gelatinases -- metabolism
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Melanoma -- drug therapy
- Neoplasm Metastasis
- Pentacyclic Triterpenes
- Triterpenes -- pharmacology
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53 -- biosynthesis
- Betulinic Acid
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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