Determination of the population pharmacokinetic parameters of sustained-release and enteric-coated oral formulations, and the suppository formulation of diclofenac sodium by simultaneous data fitting using NONMEM. [electronic resource]
Producer: 19980608Description: 169-74 p. digitalISSN:- 0142-2782
- Administration, Oral
- Anti-Inflammatory Agents, Non-Steroidal -- administration & dosage
- Biological Availability
- Computer Simulation
- Data Interpretation, Statistical
- Delayed-Action Preparations
- Diclofenac -- administration & dosage
- Dose-Response Relationship, Drug
- Gastric Mucosa -- metabolism
- Humans
- Hydrogen-Ion Concentration
- Models, Biological
- Suppositories
- Tablets, Enteric-Coated
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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