Conferring aldosterone synthesis to human CYP11B1 by replacing key amino acid residues with CYP11B2-specific ones. [electronic resource]
Producer: 19980513Description: 458-66 p. digitalISSN:- 0014-2956
- Aldosterone -- biosynthesis
- Amino Acid Sequence
- Amino Acid Substitution
- Animals
- Binding Sites
- COS Cells
- Cytochrome P-450 CYP11B2 -- chemistry
- DNA Primers
- Humans
- Hydroxylation
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Protein Structure, Secondary
- Recombinant Fusion Proteins -- chemistry
- Sequence Alignment
- Sequence Deletion
- Sequence Homology, Amino Acid
- Steroid 11-beta-Hydroxylase -- chemistry
- Transfection
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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