IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. [electronic resource]
Producer: 19980624Description: 2215-23 p. digitalISSN:- 0261-4189
- Apoptosis
- Caspase 3
- Caspase 8
- Caspase 9
- Caspases
- Cell Extracts
- Cell Line, Transformed
- Cysteine Endopeptidases -- metabolism
- Cysteine Proteinase Inhibitors -- metabolism
- Cytochrome c Group -- metabolism
- Cytosol
- Enzyme Activation
- Enzyme Precursors -- metabolism
- Humans
- Inhibitor of Apoptosis Proteins
- Protein Processing, Post-Translational
- Proteins -- metabolism
- Recombinant Fusion Proteins -- metabolism
- Tumor Cells, Cultured
- Ubiquitin-Protein Ligases
- X-Linked Inhibitor of Apoptosis Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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