Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract. [electronic resource]
Producer: 19980514Description: 9158-67 p. digitalISSN:- 0021-9258
- Amino Acid Sequence
- Apoptosis
- Ataxin-3
- Caspase 1
- Caspase 3
- Caspase 7
- Caspase 8
- Caspase 9
- Caspases
- Cysteine Endopeptidases -- metabolism
- Humans
- Huntingtin Protein
- Jurkat Cells
- Kinetics
- Nerve Tissue Proteins -- chemistry
- Neurodegenerative Diseases -- genetics
- Nuclear Proteins -- chemistry
- Osteosarcoma
- Peptides
- Receptors, Androgen -- chemistry
- Repressor Proteins
- Serine Endopeptidases -- metabolism
- Substrate Specificity
- Trinucleotide Repeats
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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