Testicular leukemia inhibitory factor (LIF) and LIF receptor mediate phosphorylation of signal transducers and activators of transcription (STAT)-3 and STAT-1 and induce c-fos transcription and activator protein-1 activation in rat Sertoli but not germ cells. [electronic resource]
Producer: 19980414Description: 1883-90 p. digitalISSN:- 0013-7227
- 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine -- pharmacology
- Animals
- DNA-Binding Proteins
- Enzyme Inhibitors -- pharmacology
- Genes, fos -- genetics
- Genistein -- pharmacology
- Growth Inhibitors -- physiology
- Interleukin-6
- Leukemia Inhibitory Factor
- Leukemia Inhibitory Factor Receptor alpha Subunit
- Lymphokines -- physiology
- Male
- Phosphorylation
- Protein Kinase Inhibitors
- RNA, Messenger -- metabolism
- Rats
- Receptors, Cytokine -- physiology
- Receptors, OSM-LIF
- STAT1 Transcription Factor
- STAT3 Transcription Factor
- Sertoli Cells -- metabolism
- Signal Transduction
- Spermatozoa -- metabolism
- Testis -- chemistry
- Trans-Activators
- Transcription Factor AP-1 -- metabolism
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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